Hereditary hearing loss: improvement by gene therapy on mouse experiment

April 6, 2015

A research team of Juntendo University and other  announced on April 6 that they succeeded in the world for the first time in an experiment of the mouse which makes the hearing convalescent by a gene therapy for the most type of hereditary hearing loss.

Hereditary hearing loss appears by the percentage of one person against about 2,000 people. There are reports on more than 60 kinds of mutation, but mutation of a "GJB2" gene also accounts for half as a cause of gene change.

The research team made the mouse that lacked a "GJB2" gene, and chipped the gene in it soon after its birth, finding the hearing ability of the mouse was improved by 10~40% compared to the mouse without the gene.  

Japanese sources:

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